The LOGICAL Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. NEJM. 2026. doi: 10.1056/NEJMoa2513814
- Related: Cardiac Arrest, Post-Cardiac Arrest
Clinical Question
- In patients who are unresponsive after cardiac arrest, does limiting oxygen exposure to achieve acceptable oxygenation increase the likelihood of surviving with a favourable functional outcome?
- Rationale: animal models suggest that hyperoxia contributes to neuronal death from overwhelming antioxidant defences
Results
