B1 Pharmacokinetics

B1.i Explain the single and multiple compartment pharmacokinetic models

B1.ii Describe the absorption of drugs and factors that influence this

B1.iii Describe the distribution of drugs and factors that influence this

B1.iv Describe the mechanisms of drug metabolism and clearance

B1.v Describe the concept of effect-site concentration

B1.vi Describe the concept of context sensitive half-time

B1.vii Compare the kinetics of an intravenous bolus dose (and dosing regimen) and a continuous infusion

B1.viii Explain clinical drug monitoring including the relevance of

B1.viii.a Peak and trough concentrations

B1.viii.b Minimum therapeutic concentrations