Part of: Mechanical Ventilation

  • Ventilator modes are just pre-set combinations of ventilator settings
  • Generally classified according to their major characteristics:
    • The control variable: pressure vs. volume
    • Breath sequence: spontaneous vs. mandatory
    • Targeting scheme: set point, dual targeting, servo control, adaptive etc.

Assist Control (AC)

  • Mix of mandatory and assisted breaths with all breaths, once triggered, are treated the same and have a consistent tidal volume
  • Trigger: time, pressure or flow
  • Control: flow (volume)
  • Cycling: time
Figure 1. Assist control. Note that the 1st, 3rd and 4th breaths are patient triggered with the second breath being time triggered.
  • Advantages
    • Guarantees a minimum minute ventilation
    • Low work of breathing
  • Disadvantages
    • Can lead to respiratory alkalosis, auto-PEEP and hypotension in hyperventilating patients as every breath leads to a fully supported breath
  • Indications
    • Critically ill patients requiring full ventilatory support and in whom fluctuations in is undesirable

Synchronised Intermittent Mandatory Ventilation (SIMV)

  • Mix of mandatory breaths (some of which are synchronised with spontaneous breaths), and assisted breaths
  • Mandatory (non-synchronised breaths):
    • Trigger: time
    • Control: flow (volume)
    • Cycling: time
  • Synchronised breaths:
    • Trigger: pressure or flow
    • Control: flow (volume)
    • Cycling: time
  • Non-synchronised breaths
    • Trigger: pressure or flow
    • Control: pressure
    • Cycling: flow
Figure 2. SIMV (with pressure support). Note that the first and fourth breaths are synchronised pressure triggered fully supported breath with tidal volume set for ~600 mL. The second, third and fifth breaths are spontaneous non-synchronised breaths assisted with pressure support with 10 cm of water.

  • User sets a rate and volume
  • There is a window of opportunity around each timed breath, during which a patient effort will be converted into a mandatory breath
  • Advantage
    • Guarantees a minimum minute ventilation
    • Lower mean airway pressure when compared with AC
    • Can provide a wide range of respiratory support
  • Disadvantages
    • Increased work of breathing for patient
    • ? Lower cardiac output in patients with LV dysfunction
  • Indications
    • Critically ill patients who are hyperventilating or otherwise prone to auto-PEEP or high airway resistance

NOTE

The main difference between SIMV and AC is that spontaneous breaths in excess of the set respiratory rate:

  • In AC receive full support
  • In SIMV receive partial support Therefore in a patient with no spontaneous breaths AC = SIMV

Pressure Control Ventilation (PCV)

  • Mandatory breaths only. The patient is unable to trigger the ventilator
  • Trigger: time
  • Control: pressure
  • Cycling: time
Figure 3. Pressure Control Ventilation. Inspiratory pressure is set at 25cm of water. Flow starts high with each breath and rapidly declines (known as a decelerating flow contour).
  • Indications
    • Patients who are at a particularly high risk of barotrauma

Pressure Support Ventilation (PSV)

  • There are no mandatory breaths; every breath must be triggered by the patient
  • Trigger: Pressure or flow
  • Control: Pressure
  • Cycling: Flow
Figure 4. Pressure support ventilation. The pressure support is set at ~15cm of water. Inspiration is terminated by the removal of pressure support once the flow drops to 25% of its maximum
  • Advantages:
    • Probably the most comfortable mode for the awake, conscious patient
  • Disadvantages:
    • Patient must trigger each breath
    • A minimum minute ventilation cannot be guaranteed
    • Associated with poorer quality sleep
    • Generally incapable of providing full ventilatory support
  • Indications
    • Conscious patient
    • As a stepping stone immediately prior to extubation

Dual Control Modes

  • Use instantaneous feedback to control aspects of lung volume and airway pressure simultaneously
  • Examples include
    • Pressure-regulated volume control
    • Volume support
    • Volume assured pressure support

Pressure Regulated Volume Control (PRVC)

  • The user sets a target tidal volume (as in volume control modes)
  • The ventilator performs an assessment of the dynamic lung compliance over the course of three initial calibrating breaths
  • Using this data, it then determines the appropriate pressure level required to achieve the prescribed tidal volume
  • Advantages:
    • Square pressure waveform favours early and sustained lung unit recruitment
    • Mean airway pressure is as high as with PCV
    • Pressure is minimised for any given prescribed tidal volume
    • A minute volume is guaranteed, preserving a degree of control over PaCO2