Part of: Mechanical Ventilation

- Ventilator modes are just pre-set combinations of ventilator settings
- Generally classified according to their major characteristics:
- The control variable: pressure vs. volume
- Breath sequence: spontaneous vs. mandatory
- Targeting scheme: set point, dual targeting, servo control, adaptive etc.
Assist Control (AC)
- Mix of mandatory and assisted breaths with all breaths, once triggered, are treated the same and have a consistent tidal volume
- Trigger: time, pressure or flow
- Control: flow (volume)
- Cycling: time
- Advantages
- Guarantees a minimum minute ventilation
- Low work of breathing
- Disadvantages
- Can lead to respiratory alkalosis, auto-PEEP and hypotension in hyperventilating patients as every breath leads to a fully supported breath
- Indications
- Critically ill patients requiring full ventilatory support and in whom fluctuations in is undesirable

Synchronised Intermittent Mandatory Ventilation (SIMV)
- Mix of mandatory breaths (some of which are synchronised with spontaneous breaths), and assisted breaths
- Mandatory (non-synchronised breaths):
- Trigger: time
- Control: flow (volume)
- Cycling: time
- Synchronised breaths:
- Trigger: pressure or flow
- Control: flow (volume)
- Cycling: time
- Non-synchronised breaths
- Trigger: pressure or flow
- Control: pressure
- Cycling: flow

- User sets a rate and volume
- There is a window of opportunity around each timed breath, during which a patient effort will be converted into a mandatory breath
- Advantage
- Guarantees a minimum minute ventilation
- Lower mean airway pressure when compared with AC
- Can provide a wide range of respiratory support
- Disadvantages
- Increased work of breathing for patient
- ? Lower cardiac output in patients with LV dysfunction
- Indications
- Critically ill patients who are hyperventilating or otherwise prone to auto-PEEP or high airway resistance
NOTE
The main difference between SIMV and AC is that spontaneous breaths in excess of the set respiratory rate:
- In AC receive full support
- In SIMV receive partial support Therefore in a patient with no spontaneous breaths AC = SIMV
Pressure Control Ventilation (PCV)
- Mandatory breaths only. The patient is unable to trigger the ventilator
- Trigger: time
- Control: pressure
- Cycling: time
- Indications
- Patients who are at a particularly high risk of barotrauma
Pressure Support Ventilation (PSV)
- There are no mandatory breaths; every breath must be triggered by the patient
- Trigger: Pressure or flow
- Control: Pressure
- Cycling: Flow
- Advantages:
- Probably the most comfortable mode for the awake, conscious patient
- Disadvantages:
- Patient must trigger each breath
- A minimum minute ventilation cannot be guaranteed
- Associated with poorer quality sleep
- Generally incapable of providing full ventilatory support
- Indications
- Conscious patient
- As a stepping stone immediately prior to extubation
Dual Control Modes
- Use instantaneous feedback to control aspects of lung volume and airway pressure simultaneously
- Examples include
- Pressure-regulated volume control
- Volume support
- Volume assured pressure support
Pressure Regulated Volume Control (PRVC)
- The user sets a target tidal volume (as in volume control modes)
- The ventilator performs an assessment of the dynamic lung compliance over the course of three initial calibrating breaths
- Using this data, it then determines the appropriate pressure level required to achieve the prescribed tidal volume
- Advantages:
- Square pressure waveform favours early and sustained lung unit recruitment
- Mean airway pressure is as high as with PCV
- Pressure is minimised for any given prescribed tidal volume
- A minute volume is guaranteed, preserving a degree of control over PaCO2