Kougias P. JAMA 2025;334:2197-2207. doi:10.1001/jama.2025.20841
- A liberal transfusion threshold (Hb <10 g/dL) compared to a restrictive transfusion threshold (Hb <7 g/dL) does not reduce 90‑day incidence of all‑cause death, major ischaemic events or acute renal failure
- Note: study population was male veterans and treating clinicians were aware of patient thresholds and may have resulted in performance bias/introduction of additional interventions
Cryopreserved vs Liquid-Stored Platelets for the Treatment of Surgical Bleeding: The CLIP-II Randomized Noninferiority Clinical Trial | Cardiothoracic Surgery | JAMA | JAMA Network Reade. JAMA, 2025. doi: 10.1001/jama.2025.23355
- Where possible liquid stored platelets should be used over cryopreserved platelets in cardiac surgical bleeding