C6.i Describe the concepts of global and regional ventilation and perfusion and:

C6.i.a describe the factors that affect these concepts,

C6.i.b describe the West’s zones of the lung and explain the mechanisms responsible for them,

C6.i.c explain V/Q matching and mismatching,

C6.i.d explain the effect of V/Q mismatch on oxygen transfer and carbon dioxide elimination.

C6.ii Define dead space and:

C6.ii.a describe its components,

C6.ii.b explain how these may be measured,

C6.ii.c describe the physiological impact of increased dead space.

C6.iii Explain the concept of shunt and:

C6.iii.a the physiological effects of shunt,

C6.iii.b how shunt may be measured.

C6.iv Define venous admixture and describe its relationship to shunt and V/Q mismatch.